Pharmaceutical Reference Standards / Impurity Standards

Methotrexate Hydrate
Methotrexate Hydrate
  • CAT. No.M160000
  • CAS. No.133073-73-1
  • Mol. F.C20H22N8O5H2O
  • Mol. W.454.44 g/mol
  • Stock Status:Instock
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Methotrexate Disodium Salt
Methotrexate Disodium Salt
  • CAT. No.M160000A
  • CAS. No.7413-34-5
  • Mol. F.C20H20N8Na2O5
  • Mol. W.498.40 g/mol
  • Stock Status:Instock
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Methotrexate base
Methotrexate base
  • CAT. No.M160000B
  • CAS. No.59-05-2
  • Mol. F.C20H22N8O5
  • Mol. W.454.44 g/mol
  • Stock Status:Under Synthesis
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Methotrexate Form 1
Methotrexate Form 1
  • CAT. No.M160000D
  • CAS. No.59-05-2
  • Mol. F.C20H22N8O5
  • Mol. W.454.43 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate EP Impurity C
Methotrexate EP Impurity C
  • CAT. No.M160001
  • CAS. No.2410-93-7
  • Mol. F.C20H21N7O6
  • Mol. W.455.44 g/mol
  • Stock Status:Instock
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Methotrexate EP Impurity J
Methotrexate EP Impurity J
  • CAT. No.M160002
  • CAS. No.34378-65-9
  • Mol. F.C22H26N8O5
  • Mol. W.482.49 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity B Hydrate
Methotrexate Impurity B Hydrate
  • CAT. No.M160003
  • CAS. No.54-62-6(free base)
  • Mol. F.C19H20N8O5.XH2O
  • Mol. W.NA
  • Stock Status:Instock
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Methotrexate EP Impurity E
Methotrexate EP Impurity E
  • CAT. No.M160004
  • CAS. No.19741-14-1
  • Mol. F.C15H15N7O2
  • Mol. W.325.33 g/mol
  • Stock Status:Instock
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Methotrexate EP Impurity D
Methotrexate EP Impurity D
  • CAT. No.M160008
  • CAS. No.5623-18-7
  • Mol. F.C15H14N6O3
  • Mol. W.326.31 g/mol
  • Stock Status:Instock
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(2,4-diaminopteridin-6-yl)methanol Hydrochloride
(2,4-diaminopteridin-6-yl)methanol Hydrochloride
  • CAT. No.M160009
  • CAS. No.73978-41-3
  • Mol. F.C7H8N6O.HCl
  • Mol. W.228.64 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate EP Impurity A
Methotrexate EP Impurity A
  • CAT. No.M160009A
  • CAS. No.945-24-4
  • Mol. F.C7H8N6O
  • Mol. W.192.18 g/mol
  • Stock Status:Instock
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2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride
2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride
  • CAT. No.M160009B
  • CAS. No.73978-41-3
  • Mol. F.C7H9ClN6O
  • Mol. W.228.64 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate EP Impurity E Hydrochloride
Methotrexate EP Impurity E Hydrochloride
  • CAT. No.M160010
  • CAS. No.70844-48-3
  • Mol. F.C30H30N14O4.HCl
  • Mol. W.1374.22 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate EP Impurity F
Methotrexate EP Impurity F
  • CAT. No.M160011
  • CAS. No.51865-79-3
  • Mol. F.C20H22N8O5
  • Mol. W.454.44 g/mol
  • Stock Status:Instock
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N-(4-N-Methylaminobenzoyl)-L-glutamic acid diethyl ester
N-(4-N-Methylaminobenzoyl)-L-glutamic acid diethyl ester
  • CAT. No.M160012
  • CAS. No.2378-95-2
  • Mol. F.C17H24N2O5
  • Mol. W.336.4 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 9
Methotrexate Impurity 9
  • CAT. No.M160013
  • CAS. No.10541-83-0
  • Mol. F.C8H9NO2
  • Mol. W.151.16 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate EP Impurity I
Methotrexate EP Impurity I
  • CAT. No.M160014
  • CAS. No.66147-29-3
  • Mol. F.C21H24N8O5
  • Mol. W.468.47 g/mol
  • Stock Status:Instock
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Methotrexate EP Impurity H
Methotrexate EP Impurity H
  • CAT. No.M160015
  • CAS. No.67022-39-3
  • Mol. F.C21H24N8O5
  • Mol. W.468.47 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Dimethylamide
Methotrexate Dimethylamide
  • CAT. No.M160016
  • CAS. No.71074-44-7
  • Mol. F.C22H27N9O4
  • Mol. W.481.51 g/mol
  • Stock Status:Instock
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4-Aminodeoxopteroic Acid
4-Aminodeoxopteroic Acid
  • CAT. No.M160017
  • CAS. No.36093-85-3
  • Mol. F.C14H13N7O2
  • Mol. W.311.3 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate EP Impurity G
Methotrexate EP Impurity G
  • CAT. No.M160018
  • CAS. No.NA
  • Mol. F.C28H29N9O6
  • Mol. W.587.59 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate EP Impurity L Disodium Salt
Methotrexate EP Impurity L Disodium Salt
  • CAT. No.M160019
  • CAS. No.NA
  • Mol. F.C13H14N2Na2O5
  • Mol. W.324.24 g/mol
  • Stock Status:Custom Synthesis
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2-amino-6-(chloromethyl) pteridin-4(1H)-one
2-amino-6-(chloromethyl) pteridin-4(1H)-one
  • CAT. No.M160020
  • CAS. No.873397-19-4
  • Mol. F.C7H6ClN5O
  • Mol. W.211.61 g/mol
  • Stock Status:Custom Synthesis
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Folic Acid Impurity 24
Folic Acid Impurity 24
  • CAT. No.M160021
  • CAS. No.712-29-8
  • Mol. F.C7H7N5O2
  • Mol. W.193.16 g/mol
  • Stock Status:Custom Synthesis
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Dimethyl Glutamate
Dimethyl Glutamate
  • CAT. No.M160022
  • CAS. No.6525-53-7
  • Mol. F.C7H13NO4
  • Mol. W.175.18 g/mol
  • Stock Status:Custom Synthesis
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(R)-Dimethyl 2-aminopentanedioate
(R)-Dimethyl 2-aminopentanedioate
  • CAT. No.M160023
  • CAS. No.16422-27-8
  • Mol. F.C7H13NO4
  • Mol. W.175.2 g/mol
  • Stock Status:Custom Synthesis
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D-glutamic Acid Diethyl Ester
D-glutamic Acid Diethyl Ester
  • CAT. No.M160024
  • CAS. No.13107-55-6
  • Mol. F.C9H17NO4
  • Mol. W.203.24 g/mol
  • Stock Status:Custom Synthesis
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(4S)-4-amino-5-(dimethylamino)-5-oxopentanoic acid
(4S)-4-amino-5-(dimethylamino)-5-oxopentanoic acid
  • CAT. No.M160025
  • CAS. No.87733-70-8
  • Mol. F.C7H14N2O3
  • Mol. W.174.21 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate 7-Hydroxy
Methotrexate 7-Hydroxy
  • CAT. No.M160026
  • CAS. No.5939-37-7
  • Mol. F.C20H22N8O6
  • Mol. W.470.44 g/mol
  • Stock Status:Custom Synthesis
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2,4-Diaminopteridine
2,4-Diaminopteridine
  • CAT. No.M160028
  • CAS. No.1127-93-1
  • Mol. F.C6H6N6
  • Mol. W.162.15 g/mol
  • Stock Status:Instock
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2,4-Diamino-6-methylpteridine
2,4-Diamino-6-methylpteridine
  • CAT. No.M160029
  • CAS. No.708-74-7
  • Mol. F.C7H8N6
  • Mol. W.176.18 g/mol
  • Stock Status:Under Synthesis
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N-(4-chlorobenzoyl)-L-glutamic Acid
N-(4-chlorobenzoyl)-L-glutamic Acid
  • CAT. No.M160030
  • CAS. No.57444-70-9
  • Mol. F.C12H12ClNO5
  • Mol. W.285.7 g/mol
  • Stock Status:Custom Synthesis
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Diethyl 2-(4-aminobenzamido)pentanedioate
Diethyl 2-(4-aminobenzamido)pentanedioate
  • CAT. No.M160031
  • CAS. No.NA
  • Mol. F.C16H22N2O5
  • Mol. W.322.36g/mol
  • Stock Status:Custom Synthesis
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Diethyl(2S)-2-((4-(ethylamino)benzoyl)amino)pentanedioate
Diethyl(2S)-2-((4-(ethylamino)benzoyl)amino)pentanedioate
  • CAT. No.M160032
  • CAS. No.NA
  • Mol. F.C18H26N2O5
  • Mol. W.350.41 g/mol
  • Stock Status:Custom Synthesis
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Diethyl(2S)-2-((2-(methylamino)benzoyl)amino)pentanedioate
Diethyl(2S)-2-((2-(methylamino)benzoyl)amino)pentanedioate
  • CAT. No.M160033
  • CAS. No.NA
  • Mol. F.C17H24N2O5
  • Mol. W.336.38 g/mol
  • Stock Status:Custom Synthesis
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Diethyl(2S)-2-((3-(methylamino)benzoyl)amino)pentanedioate
Diethyl(2S)-2-((3-(methylamino)benzoyl)amino)pentanedioate
  • CAT. No.M160034
  • CAS. No.NA
  • Mol. F.C17H24N2O5
  • Mol. W.336.38 g/mol
  • Stock Status:Custom Synthesis
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2,4-diamino-7-methylpteridine hemi hydrochloride
2,4-diamino-7-methylpteridine hemi hydrochloride
  • CAT. No.M160036
  • CAS. No.NA
  • Mol. F.C7H8N6.1/2(HCl)
  • Mol. W.194.41 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate EP Impurity L
Methotrexate EP Impurity L
  • CAT. No.M160038
  • CAS. No.52980-68-4
  • Mol. F.C13H16N2O5
  • Mol. W.280.28 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Methotrexate
N-Nitroso Methotrexate
  • CAT. No.M160039
  • CAS. No.NA
  • Mol. F.C13H15N3O6
  • Mol. W.309.27 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Dimethylester Hydrochloride
Methotrexate Dimethylester Hydrochloride
  • CAT. No.M160040
  • CAS. No.NA
  • Mol. F.C22H27ClN8O5
  • Mol. W.518.95 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Methotrexate EP Impurity-B
N-Nitroso Methotrexate EP Impurity-B
  • CAT. No.M160041
  • CAS. No.NA
  • Mol. F.C19H19N9O6
  • Mol. W.469.41 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Methotrexate EP Impurity L
N-Nitroso Methotrexate EP Impurity L
  • CAT. No.M160042
  • CAS. No.NA
  • Mol. F.C13H15N3O6
  • Mol. W.309.27 g/mol
  • Stock Status:Custom Synthesis
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N-(4-(methyl(nitroso)amino)benzoyl)-N-nitroso-L-glutamic acid
N-(4-(methyl(nitroso)amino)benzoyl)-N-nitroso-L-glutamic acid
  • CAT. No.M160043
  • CAS. No.NA
  • Mol. F.C13H14N4O7
  • Mol. W.338.27 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 4
Methotrexate Impurity 4
  • CAT. No.M160044
  • CAS. No.52030-86-1
  • Mol. F.C13H16N2O5
  • Mol. W.280.28 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 11
Methotrexate Impurity 11
  • CAT. No.M160045
  • CAS. No.34794-87-1
  • Mol. F.C15H14N6O3
  • Mol. W.326.31 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 12
Methotrexate Impurity 12
  • CAT. No.M160046
  • CAS. No.881-33-4
  • Mol. F.C7H8N6O
  • Mol. W.192.18 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso S-Methylaminobenzoyl Glutamicester
N-Nitroso S-Methylaminobenzoyl Glutamicester
  • CAT. No.M160047
  • CAS. No.NA
  • Mol. F.C17H23N3O6
  • Mol. W.365.38 g/mol
  • Stock Status:Custom Synthesis
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(R)-diethyl-2-(4-(methyl(nitroso)amino)benzamido)pentanedioate
(R)-diethyl-2-(4-(methyl(nitroso)amino)benzamido)pentanedioate
  • CAT. No.M160048
  • CAS. No.NA
  • Mol. F.C17H23N3O6
  • Mol. W.365.38 g/mol
  • Stock Status:Custom Synthesis
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(S)-2-(4-(N-((2,4-diaminopteridin-6-yl)methyl)formamido)benzamido)pentanedioic acid
(S)-2-(4-(N-((2,4-diaminopteridin-6-yl)methyl)formamido)benzamido)pentanedioic acid
  • CAT. No.M160049
  • CAS. No.NA
  • Mol. F.C20H20N8O6
  • Mol. W.468.42 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 13
Methotrexate Impurity 13
  • CAT. No.M160050
  • CAS. No.NA
  • Mol. F.C15H20N2O5
  • Mol. W.308.33 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 14
Methotrexate Impurity 14
  • CAT. No.M160051
  • CAS. No.NA
  • Mol. F.C15H20N2O5
  • Mol. W.308.33 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 15
Methotrexate Impurity 15
  • CAT. No.M160052
  • CAS. No.NA
  • Mol. F.C22H26N8O5
  • Mol. W.482.49 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 16
Methotrexate Impurity 16
  • CAT. No.M160053
  • CAS. No.65148-63-2
  • Mol. F.C22H26N8O5
  • Mol. W.482.49 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity B Disodium Salt
Methotrexate Impurity B Disodium Salt
  • CAT. No.M160054
  • CAS. No.NA
  • Mol. F.C19H18N8Na2O5
  • Mol. W.484.38 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Methotrexate
N-Nitroso Methotrexate
  • CAT. No.M160055
  • CAS. No.NA
  • Mol. F.C20H21N9O6
  • Mol. W.483.44 g/mol
  • Stock Status:Custom Synthesis
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4-Aminobenzoyl D-Glutamic Acid
4-Aminobenzoyl D-Glutamic Acid
  • CAT. No.M160056
  • CAS. No.5959-18-2
  • Mol. F.C12H14N2O5
  • Mol. W.266.25 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 6
Methotrexate Impurity 6
  • CAT. No.M160057
  • CAS. No.NA
  • Mol. F.C8H10N6O2
  • Mol. W.222.20 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Methotrexate EP Impurity B D6
N-Nitroso Methotrexate EP Impurity B D6
  • CAT. No.M160058
  • CAS. No.NA
  • Mol. F.C19H13D6N9O6
  • Mol. W.475.45 g/mol
  • Stock Status:Custom Synthesis
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(S)-1-ethyl 5-methyl 2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioate
(S)-1-ethyl 5-methyl 2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioate
  • CAT. No.M160059
  • CAS. No.NA
  • Mol. F.C23H28N8O5
  • Mol. W.496.52 g/mol
  • Stock Status:Custom Synthesis
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(S)-5-ethyl 1-methyl2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioate
(S)-5-ethyl 1-methyl2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioate
  • CAT. No.M160060
  • CAS. No.NA
  • Mol. F.C23H28N8O5
  • Mol. W.496.52 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Diethyl Ester
Methotrexate Diethyl Ester
  • CAT. No.M160061
  • CAS. No.43170-88-3
  • Mol. F.C24H30N8O5
  • Mol. W.510.55 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Hydrate EP Impurity B
Methotrexate Hydrate EP Impurity B
  • CAT. No.M160062
  • CAS. No.1217459-90-9
  • Mol. F.C19H22N8O6
  • Mol. W.458.43 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate EP Impurity B
Methotrexate EP Impurity B
  • CAT. No.M160063
  • CAS. No.54-62-6
  • Mol. F.C19H20N8O5
  • Mol. W.440.41 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 20 Sulfate
Methotrexate Impurity 20 Sulfate
  • CAT. No.M160064
  • CAS. No.5392-28-9
  • Mol. F.C4H8N6.H2O4S
  • Mol. W.238.23 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 5
Methotrexate Impurity 5
  • CAT. No.M160066
  • CAS. No.4215-07-0
  • Mol. F.C7H8N6
  • Mol. W.176.18 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 3
Methotrexate Impurity 3
  • CAT. No.M160067
  • CAS. No.57963-63-0
  • Mol. F.C16H21NO6
  • Mol. W.323.34 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 7
Methotrexate Impurity 7
  • CAT. No.M160068
  • CAS. No.NA
  • Mol. F.C18H26N2O5
  • Mol. W.350.41 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 8
Methotrexate Impurity 8
  • CAT. No.M160069
  • CAS. No.115827-03-7
  • Mol. F.C24H30N2O5
  • Mol. W.426.51 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 10
Methotrexate Impurity 10
  • CAT. No.M160070
  • CAS. No.NA
  • Mol. F.C30H30N2O7
  • Mol. W.530.57 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 17
Methotrexate Impurity 17
  • CAT. No.M160071
  • CAS. No.NA
  • Mol. F.C16H20ClNO5
  • Mol. W.341.79 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 18
Methotrexate Impurity 18
  • CAT. No.M160072
  • CAS. No.NA
  • Mol. F.C17H22N2O6
  • Mol. W.350.37 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 19
Methotrexate Impurity 19
  • CAT. No.M160073
  • CAS. No.909874-43-7
  • Mol. F.C18H26N2O5
  • Mol. W.350.41 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 1
Methotrexate Impurity 1
  • CAT. No.M160075
  • CAS. No.1308957-12-1
  • Mol. F.C12H12ClNO5
  • Mol. W.285.68 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 2
Methotrexate Impurity 2
  • CAT. No.M160076
  • CAS. No.87039-96-1
  • Mol. F.C12H12ClNO5
  • Mol. W.285.68 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 21
Methotrexate Impurity 21
  • CAT. No.M160077
  • CAS. No.67278-37-9
  • Mol. F.C14H18N2O5
  • Mol. W.294.30 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 22
Methotrexate Impurity 22
  • CAT. No.M160078
  • CAS. No.79974-20-2
  • Mol. F.C14H18N2O5
  • Mol. W.294.30 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 23
Methotrexate Impurity 23
  • CAT. No.M160079
  • CAS. No.79974-19-9
  • Mol. F.C14H18N2O5
  • Mol. W.294.30 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 24
Methotrexate Impurity 24
  • CAT. No.M160080
  • CAS. No.101810-76-8
  • Mol. F.C15H20N2O5
  • Mol. W.308.33 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 25
Methotrexate Impurity 25
  • CAT. No.M160081
  • CAS. No.942840-87-1
  • Mol. F.C9H12N2O
  • Mol. W.164.20 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 26
Methotrexate Impurity 26
  • CAT. No.M160082
  • CAS. No.54643-27-5
  • Mol. F.C7H8N6O2
  • Mol. W.208.18 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 27
Methotrexate Impurity 27
  • CAT. No.M160083
  • CAS. No.4261-17-0
  • Mol. F.C7H6N6O
  • Mol. W.190.16 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 28
Methotrexate Impurity 28
  • CAT. No.M160084
  • CAS. No.NA
  • Mol. F.C8H10N6O
  • Mol. W.206.20 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 29
Methotrexate Impurity 29
  • CAT. No.M160085
  • CAS. No.41600-13-9
  • Mol. F.C25H29N9O8
  • Mol. W.583.55 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 30
Methotrexate Impurity 30
  • CAT. No.M160086
  • CAS. No.52980-66-2
  • Mol. F.C20H22N8O5
  • Mol. W.454.44 g/mol
  • Stock Status:Custom Synthesis
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Methotrexate Impurity 31
Methotrexate Impurity 31
  • CAT. No.M160087
  • CAS. No.142645-42-9
  • Mol. F.C7H7N5O
  • Mol. W.177.16 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Methotrexate-D3
Methotrexate-D3
  • CAT. No.M160005
  • CAS. No.432545-63-6
  • Mol. F.C20H19D3N8O5
  • Mol. W.457.46 g/mol
  • Stock Status:Instock
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Methotrexate -13C,D3
Methotrexate -13C,D3
  • CAT. No.M160037
  • CAS. No.1786417-03-5
  • Mol. F.C1913CH19D3N8O5
  • Mol. W.458.45 g/mol
  • Stock Status:Instock
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